The museum was founded in 1999 by Bishop Dionysios the first and it operates under the supervision of the Holy Metropolis of Drama. It is located in the city center, in a newly renovated five-story building of the Episcopal Palace.
In the rooms of the museum someone can see important artifacts that refugees from Pontos and Minor Asia brought with them. Amongst them, there are icons of the Virgin Mary and the Saints made during the 13th century.
Its rich collection of exhibits includes portable icons, wood carvings, gild-embroidered covers, and ecclesiastical utensils which are rare relics of exceptional art. Probably the most important exhibit is the hierarchical vestments of the National Martyr Metropolitan of Smyrna Chrysostomos.